ZIC SC 010353 (ZIC) | |||
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Title | Experimental Therapeutics of Pediatric Hematopoietic Malignancies | ||
Institution | NCI, Bethesda, MD | ||
Principal Investigator | Wayne, Alan | NCI Program Director | N/A |
Cancer Activity | N/A | Division | CCR |
Funded Amount | $854,426 | Project Dates | 10/01/2000 - N/A |
Fiscal Year | 2009 | Project Type | Intramural |
Research Topics w/ Percent Relevance | Cancer Types w/ Percent Relevance | ||
Bone Marrow Transplantation (50.0%) Cancer (100.0%) Chemotherapy (50.0%) Childhood Cancers (90.0%) Organ Transplantation Research (50.0%) |
Childhood Leukemia (90.0%) Hodgkins disease (5.0%) Leukemia (90.0%) Non Hodgkins Lymphoma (5.0%) |
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Research Type | |||
Systemic Therapies - Discovery and Development Systemic Therapies - Clinical Applications |
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Abstract | |||
The primary goal is to develop new treatments for childhood leukemias and lymphomas. The following projects are currently underway or in preparation: 1) Anti-CD22 Immunotoxins for Treatment of Leukemias and Lymphomas in Childhood 2) Pilot Study of Non-Myeloablative, HLA-Matched Allogeneic Stem Cell Transplantation in Pediatric Leukemias and Lymphomas 3) Unconjugated Monoclonal Antibodies for Treatment Lymphomas In Childhood 4) EPOCH-Rituximab for HIV-Associated Non-Hodgkin's Lymphomas In Childhood 5) Phase II Study of UCN-01 In Relapsed Or Refractory Systemic Anaplastic Large Cell And Mature T-Cell Lymphomas 6) WT1 Peptide-Transduced Allogeneic Dendritic Cell Vaccine for Hematologic Malignancies 7) Hematologic Malignancy Biology Study |